FASTQ Compression

Stop paying full price for FASTQ storage

Our 4BIN encoder compresses FASTQ files to 4.5% of original size — losslessly. That's 95.5% less S3, GCS, or Azure storage spend. No data loss. Ever.

Genomic data is eating your budget

storage

200 GB per genome

A single whole-genome sequencing run produces 100–300 GB of raw FASTQ. Multiply by thousands of samples and you're looking at petabytes.

trending_up

Data never stops growing

Sequencing output doubles every 12 months. Your storage bill grows with it — gzip only compresses to ~25% and can't keep up.

payments

$23,000/PB/month on S3

At $0.023/GB, storing 1 petabyte of raw FASTQ costs $23,000 every month. That's $276,000 per year — just for storage.

4.5%
Of original size
22x
Compression ratio
100%
Lossless
1.15x
Better than PetaGene

Benchmarked against real sequencing data

Three datasets from the DDBJ Sequence Read Archive. Fully lossless — decompressed output is bit-identical to the original.

Dataset 4BIN PetaGene gzip Result
DRR000798 4.56% ~5.3% ~25% 1.16x better than PetaGene
DRR000801 4.77% ~5.3% ~25% 1.11x better than PetaGene
DRR000802 4.47% ~5.3% ~25% 1.19x better than PetaGene

How much would you save?

Annual S3 storage costs at $0.023/GB/month for raw FASTQ vs 4BIN compressed.

Raw Data Before (gzip) After (4BIN) Annual Savings
10 TB $690/yr $124/yr $566/yr
100 TB $6,900/yr $1,242/yr $5,658/yr
1 PB $69,000/yr $12,420/yr $56,580/yr
10 PB $690,000/yr $124,200/yr $565,800/yr

Before column assumes gzip compression (~25% of raw). 4BIN compresses to 4.5% of raw — an 82% reduction over gzip.

Built for clinical and research-grade data

verified

Bit-perfect lossless

Every base call, quality score, and read header decompresses to the exact original. Zero bits lost.

security

HIPAA compatible

Data stays in your cloud environment. We provide the encoder — your data never leaves your infrastructure.

speed

Fast decompression

Decompress at disk speed. No bottleneck before your analysis pipeline starts. Compatible with existing FASTQ toolchains.

cloud_download

95% less egress

Transfer a 200 GB genome as 9 GB. Faster uploads from sequencers, faster downloads for analysis.

"Switching from gzip to 4BIN reduced our sequencing archive from 2.4 PB to 108 TB — saving us over $600,000 per year in S3 costs alone."

— Genomics Infrastructure Lead, Mid-size Biotech

Start compressing FASTQ files today

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