Store FASTQ files at 50% less than S3
5x smaller than gzip. 100% lossless. Bit-identical decompression. Upload via API or browser.
Benchmarked on real sequencing data
DDBJ Sequence Read Archive datasets. Decompressed output is bit-identical to the original.
| Dataset | 4BIN | PetaGene | gzip | Result |
|---|---|---|---|---|
| DRR000798 | 4.56% | ~5.3% | ~25% | 1.16x better than PetaGene |
| DRR000801 | 4.77% | ~5.3% | ~25% | 1.11x better than PetaGene |
| DRR000802 | 4.47% | ~5.3% | ~25% | 1.19x better than PetaGene |
How it works
Upload FASTQ
Drag your .fastq or .fastq.gz file into the browser, or use the API / CLI.
We compress it
Our 4BIN encoder stores your data at 50% less than AWS, Google, and Azure. Lossless. Takes seconds.
Download or store
Download the original file and save 50% data storage costs.
Compatible with your pipeline
Bit-perfect lossless
Every base call, quality score, and read header decompresses to the exact original. SHA-256 verified.
REST API + CLI
Integrate with curl, Python, or any HTTP client. Scriptable for batch pipelines.
FASTQ, BAM, VCF, POD5
Supports all major sequencing formats. Paired reads, Illumina, ONT, PacBio data.
HIPAA compatible
Data encrypted in transit and at rest. SOC 2 Type II aligned security practices.
Start in 30 seconds
curl -X POST https://smallest.zip/api/dna/upload \
-H "x-api-key: YOUR_API_KEY" \
-F "file=@sample.fastq" \
-F "format=fastq"curl https://smallest.zip/api/files/UPLOAD_ID/download \
-H "x-api-key: YOUR_API_KEY" \
-o restored.fastqHow much would you save?
Annual S3 storage costs at $0.023/GB/month — raw FASTQ vs 4BIN compressed.
| Raw Data | Before (gzip) | After (4BIN) | Annual Savings |
|---|---|---|---|
| 10 TB | $690/yr | $124/yr | $566/yr |
| 100 TB | $6,900/yr | $1,242/yr | $5,658/yr |
| 1 PB | $69,000/yr | $12,420/yr | $56,580/yr |
| 10 PB | $690,000/yr | $124,200/yr | $565,800/yr |
Before column assumes gzip (~25% of raw). 4BIN stores at 50% less than AWS, Google, and Azure.
See how much your lab would save
Send us a sample FASTQ file and we'll send back a free compression report showing your exact savings vs gzip, S3, and Glacier.